Naslov
Relationship of history data, clinical findings and tracheal wash culture in horses with chronic respiratory disease

Autori
Štritof, Zrinka ; Csik, Goran ; Gotić, Jelena ; Brkljača Bottegaro, Nika ; Habuš, Josipa ; Grden, Darko ; Hadina, Suzana ; Perharić, Matko ; Turk Nenad

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
World equine airway symposium 2017 Proceedings / - , 2017, 140-140

Skup
World equine airway symposium 2017

Mjesto i datum
Kopenhagen, Danska, 12.07.2017. - 15.07.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Respiratory disease ; tracheal wash ; bacteria ; horse

Sažetak
Introduction Chronic respiratory diseases in horses develop as a consequence of infectious, allergic or parasitic causes. Horses are often empirically treated with antimicrobials, However, due to increasing antimicrobial resistance problem, their use should be justified. Antimicrobial therapy is indicated in lower respiratory tract (LRT) bacterial infection but its recognition based on clinical presentation may not always be straightforward. Objectives The objective of this retrospective study was to analyse history and clinical data from horses with chronic respiratory disease and assess the relationship between the incidence of the particular history and clinical parameters and the isolation of bacteria from tracheal wash. Methods This study includes data from 42 cases of chronic respiratory disease in adult horses. History data, clinical signs, endoscopy findings and results of tracheal wash culture were analysed. History data included coughing, breathing difficulty, nasal secretions, bloody discharge from the nares, fever, previous antimicrobial therapy and vaccination against influenza. Clinical parameters included fever, increased heart rate and respiration frequency, mucosal hyperemia, enlarged lymph nodes, altered auscultatory findings, elevated white blood count and cough provocation test while endoscopy parameters included hyperemia and presence of mucus in pharinx, hiperemia and presence of mucus in trachea and amount of mucus in trachea. Tracheal washes were plated on sheep blood agar and incubated aerobically for 24 hours at 37 °C. Only abundant growth of pure bacterial culture was considered significant and declared positive. For the purpose of the study, horses were divided into two groups: those with positive and those with negative tracheal wash cultures. The incidence of the particular history and clinical data were investigated within each group. Statistical significance was assessed by using chi-square and Fisher's exact test. Results The most frequently recorded history data were coughing (95.2%), previous antimicrobial therapy (62.0%) and breathing difficulty (52.4%), while the most frequently observed clinical signs were cough provocation (83.3%), breathing difficulty (54.8%), increased respiration frequency (54.8%) and abnormal lung sounds (50.0%). Bacteria were isolated from a tracheal wash of 19/42 (45.2 %) horses. In 11/19 (57.9%) cases gram-negative (Actinobacillus equuli, Pasteurella caballi, Klebsiella sp., Acinetobacter sp.), while in 8/19 (42.1%) cases gram-positive bacteria (Streptococcus sp., Staphylococcus sp.) were isolated. In the group of horses with positive tracheal wash culture, higher incidence of the three parameters (previous antimicrobial therapy, abnormal lung sounds and a greater amount of tracheal mucus) were recorded (p<0.05). Conclusion There was a greater likelihood of isolation of bacteria from tracheal wash in horses previously treated with antibiotics, in horses with abnormal lung sounds and those with increased amount of tracheal mucus. Therefore, the presence of these parameters emphasises the need for tracheal wash bacteriological examination and adequate antimicrobial therapy.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA