Pregled bibliografske jedinice broj: 881202
MicroRNAs as cancer therapeutics: A step closer to clinical application
microRNAs as cancer therapeutics: A step closer to clinical application // Cancer letters, 407 (2017), 113-122 doi:10.1016/j.canlet.2017.04.007 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 881202 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
MicroRNAs as cancer therapeutics: A step closer to clinical application
Autori
Catela Ivković, Tina ; Voss, Gjendine ; Cornella, Helena ; Ceder, Yvonne
Izvornik
Cancer letters (0304-3835) 407
(2017);
113-122
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Metastases ; Therapy resistance ; Drug delivery ; miR-34a ; miR-15/16 ; miR-155
Sažetak
During the last decades, basic and translational research has enabled great improvements in the clinical management of cancer. However, scarcity of complete remission and many drug-induced toxicities are still a major problem in the clinics. Recently, microRNAs (miRNAs) have emerged as promising therapeutic targets due to their involvement in cancer development and progression. Their extraordinary regulatory potential, which enables regulation of entire signalling networks within the cells, makes them an interesting tool for the development of cancer therapeutics. In this review we will focus on miRNAs with experimentally proven therapeutic potential, and discuss recent advances in the technical development and clinical evaluation of miRNA-based therapeutic agents.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
098-0982464-2508 - Molekularna genetika i farmakogenetika gastrointestinalnih tumora (Kapitanović, Sanja, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Profili:
Tina Catela Ivković
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE