Naslov
Lipid profile, glucose and homocysteine levels in pregnant women from the cribs study - the preliminary report

Autori
Zajc Petranović, Matea ; Havaš Auguštin, Dubravka ; Novokmet, Natalija ; Pribačić Ambrožić, Vanda ; Perinić Lewis, Ana ; Šarac, Jelena ; Carić, Tonko ; Sindik, Joško ; Čoklo, Miran ; Karelović, Deni ; Škrabić, Veselin ; Žižić, Ana ; Stanišić, Lada ; Orehovec, Biserka ; Romić, Željko ; Janković, Stipan ; Missoni, Saša

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
9th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy of which Maternal Medicine meets Fetal Medicine

Mjesto i datum
Barcelona, Španjolska, 08.03.2017. - 11.03.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
CRIBS ; pregnancy ; newborn ; cholesterol ; triglycerides ; glucose ; homocysteine ; anthropometry

Sažetak
The intrauterine environment affects fetal growth and development. Healthy women with no history of chronic diseases, who concieved naturally and had singleton pregnancies have been participating in the CRoatian Islands` Birth Cohort Study (CRIBS), an ongoing project in the Eastern Adriatic, Croatia, aiming to assess the prevalence of risk factors for the Metabolic Syndrom. Fasting blood lipids (tot- Chol, Trig, HDL-Chol and LDL-Chol), glucose and homocysteine levels were determined in 94 pregnant women (taken between 22th and 26th week of gestation). We investigated their association with possible predisposing factors (age, gestational age, level of education, obesity and smoking status), newborns` anthropometric measures (weight, lenght and head circumference) and with adverse pregnancy outcomes (pre-eclampsia, preterm birth, small/large for gestational age). Among the blood lipids, the largest divergence was found in triglyceride levels (mean 4.2±1.1, range 0.9-11), with elevated values (>1.7 mmol/L) present in >75% of the examinees. Smokers, in comparison to non-smokers, had significantly lower HDL-Chol levels and women older than 30 years had significantly higher tot-Chol than younger ones. Women with higher mean glucose levels (but within the normal range) gave birth to children with significantly higher weight- at-birth z-standardized according to WHO, and women with low homocysteine levels (<3.4 μmol/L) gave birth to children with higher z- standardized BMI. None of the blood parameters was associated with any of the pregnancy outcome measures. The modification of lifestyle during the pregnancy might help in regulating blood lipids, glucose and homocysteine levels, what would in return positively affect the body size of newborns.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Javno zdravstvo i zdravstvena zaštita, Etnologija i antropologija

POVEZANOST RADA