Screening of six medicinal plant extracts obtained by two conventional methods and supercritical CO2 extraction targeted on coumarin content, 2, 2-diphenyl-1- picrylhydrazyl radical scavenging capacity and total phenols content

Molnar, Maja; Jerković, Igor; Suknović, Dragica; Bilić Rajs, Blanka; Aladić, Krunoslav; Šubarić, Drago; Jokić, Stela

doi:10.3390/molecules22030348

Pregled bibliografske jedinice broj: 862707

Screening of six medicinal plant extracts obtained by two conventional methods and supercritical CO2 extraction targeted on coumarin content, 2, 2-diphenyl-1- picrylhydrazyl radical scavenging capacity and total phenols content

Molnar, Maja; Jerković, Igor; Suknović, Dragica; Bilić Rajs, Blanka; Aladić, Krunoslav; Šubarić, Drago; Jokić, Stela

Screening of six medicinal plant extracts obtained by two conventional methods and supercritical CO2 extraction targeted on coumarin content, 2, 2-diphenyl-1- picrylhydrazyl radical scavenging capacity and total phenols content // Molecules, 22 (2017), 3; 348, 10 doi:10.3390/molecules22030348 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 862707 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Screening of six medicinal plant extracts obtained by two conventional methods and supercritical CO2 extraction targeted on coumarin content, 2, 2-diphenyl-1- picrylhydrazyl radical scavenging capacity and total phenols content

Autori
Molnar, Maja ; Jerković, Igor ; Suknović, Dragica ; Bilić Rajs, Blanka ; Aladić, Krunoslav ; Šubarić, Drago ; Jokić, Stela

Izvornik
Molecules (1420-3049) 22 (2017), 3; 348, 10

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
medicinal plants ; extraction ; SC-CO2 ; coumarin ; antiradical capacity

Sažetak
Six medicinal plants Helichrysum italicum (Roth) G. Don, Angelica archangelica L., Lavandula officinalis L., Salvia officinalis L., Melilotus officinalis L., and Ruta graveolens L. were used. The aim of the study was to compare their extracts obtained by Soxhlet (hexane) extraction, maceration with ethanol (EtOH), and supercritical CO2 extraction (SC-CO2) targeted on coumarin content (by high performance liquid chromatography with ultraviolet detection, HPLC-UV), 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging capacity, and total phenols (TPs) content (by Folin–Ciocalteu assay). The highest extraction yields were obtained by EtOH, followed by hexane and SC- CO2. The highest coumarin content (316.37 mg/100 g) was found in M. officinalis EtOH extracts, but its SC-CO2 extraction yield was very low for further investigation. Coumarin was also found in SC-CO2 extracts of S. officinalis, R. graveolens, A. archangelica, and L. officinalis. EtOH extracts of all plants exhibited the highest DPPH scavenging capacity. SC-CO2 extracts exhibited antiradical capacity similar to hexane extracts, while S. officinalis SC-CO2 extracts were the most potent (95.7%). EtOH extracts contained the most TPs (up to 132.1 mg gallic acid equivalents (GAE)/g from H. italicum) in comparison to hexane or SC-CO2 extracts. TPs content was highly correlated to the DPPH scavenging capacity of the extracts. The results indicate that for comprehensive screening of different medicinal plants, various extraction techniques should be used in order to get a better insight into their components content or antiradical capacity.

Izvorni jezik
Engleski

Znanstvena područja
Kemijsko inženjerstvo, Farmacija, Biotehnologija

POVEZANOST RADA

Projekti:
HRZZ-IP-2013-11-8547 - Istraživaje prirodnih spojeva i aroma: kemijsko profiliranje i otkrivanje potecijala (NaPro-Flav) (Jerković, Igor, HRZZ - 2013-11) ( CroRIS)

Ustanove:
Kemijsko-tehnološki fakultet, Split,
Hrvatski veterinarski institut, Zagreb,
Prehrambeno-tehnološki fakultet, Osijek,
Klinički bolnički centar Osijek

Profili:

Igor Jerković (autor)