Naslov
Low 25-hydroxyvitamin D levels in vitiligo

Autori
Jerković Gulin, S ; Chiriac, Anca E ; Foia, Liliana ; Chiriac, Anca

Izvornik
European Journal of Pediatric Dermatology (English Ed.) (1122-7672) 26 (2016), 3; 162-163

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
vitamin D, vitiligo
(vitimin D, vitiligo)

Sažetak
Evaluation of serum 25-hydroxyvitamin D levels in patients diagnosed with vitiligo is still controversial, although a significant association has been proved in recent studies, but no correlation with causality or/and prognosis after vitamin D supplementation. We present a case of a 24-year-old male student, with indoor activities, diagnosed with facial vitiligo at the age of 11. Initially, lesions faded during winter time, slight erythema and white small macules being observed around the eyes during summer days. He presented with large vitiligo patches on the face, neck, and trunk. Clinical examination confirmed the diagnosis of vitiligo. The family history of other autoimmune disease was negative. Extended laboratory investigations proved to be within normal limits, no signs of other autoimmune disorder were detected. The serum level of 25-hydroxyvitamin D was 9.4 ng/ ml (normal values between 30 and 100 ng/ml). Topical steroids were recommended in combination with nbUVB (311 nm) phototherapy (30 sessions). No improvement of skin lesion was noticed and the serum level of 25- hydroxyvitamin D remained low. Emollients proved to be less effective to the skin lesions and despite vitamin D supplementation, the serum level of 25-hydroxyvitamin D persisted low for the following 6 months. The evaluations were made by the same laboratory ; repeated endocrine examination did not reveal any abnormality. No statistical data regarding the serum levels of 25-hydroxyvitamin D within the normal population in the same geographical area with our patient exists, thus no conclusions can be made. Presented case is an alarm signal to monitor all vitiligo patients by verifying the serum levels of 25-hydroxyvitamin D at every medical visit and to compare the data within the normal population

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA