Pregled bibliografske jedinice broj: 856145
Ubiquitous Importance of Protein Glycosylation
Ubiquitous Importance of Protein Glycosylation // High-Throughput Glycomics and Glycoproteomics / Lauc, Gordan ; Wuhrer, Manfred (ur.).
New York (NY): Springer, 2017. str. 1-12
CROSBI ID: 856145 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Ubiquitous Importance of Protein Glycosylation
Autori
Krištić, Jasminka ; Lauc, Gordan
Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni
Knjiga
High-Throughput Glycomics and Glycoproteomics
Urednik/ci
Lauc, Gordan ; Wuhrer, Manfred
Izdavač
Springer
Grad
New York (NY)
Godina
2017
Raspon stranica
1-12
ISBN
978-1-4939-6491-8
Ključne riječi
Alternative glycosylation ; Glycans ; Glycosylation in disease ; IgG glycosylation ; Lectins ; O-GlcNAc ; Protein function ; Protein half-life ; Protein structure
Sažetak
More than half of all proteins are glycosylated. The attached glycans provide proteins with important structural and functional properties and glycan parts of glycoproteins have essential roles in many key biological processes. This chapter describes the effect of glycosylation on the structure and function of proteins, with emphasis on regulation of protein half-life and modulation of protein function by alternative glycosylation. In addition, this chapter highlights the importance of glycan-lectin interactions, the ability of glycans to block phosphorylation of proteins, and the importance of glycans in disease.
Izvorni jezik
Engleski
