Naslov
Pan Drug-Resistant Environmental Isolate of Acinetobacter baumannii from Croatia

Autori
Goić-Barišić, Ivana ; Šeruga Musić, Martina ; Kovačić, Ana ; Tonkić, Marija ; Hrenović, Jasna

Izvornik
Microbial drug resistance-mechanisms epidemiology and disease (1076-6294) 23 (2017), 4; 494-496

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Acinetobacter ; blaOXA gene ; effluent wastewater ; multidrug resistance ; plasmid

Sažetak
Acinetobacter baumannii is an emerging nosocomial pathogen with also emerging resistance to different antibiotics. Multidrug and pan drug-resistant clinical isolates were reported worldwide. Here we report the first evidence of pan drug-resistant environmental isolate of A. baumannii. The isolate was recovered from the effluent of secondary treated municipal wastewater of the City of Zagreb, Croatia. The isolate was resistant to penicillins/b-lactamase inhibitors, carbapenems, fluoroquinolones, aminoglycosides, folate pathway inhibitors, and polymyxins, except intermediately susceptible to minocycline and tigecycline. Intrinsic chromosomally located blaOXA-51-like gene and acquired plasmid-located blaOXA-23-like gene were related to clinical isolates. Pan drug-resistant A. baumannii can occur in natural environments outside of the hospital. Secondary treated municipal wastewater represents a potential epidemiological reservoir of pan drug-resistant A. baumannii and carbapenem resistance gene.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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