Naslov
Cytogenetic damage in exfoliated oral buccal cells by dental composites

Autori
Tadin, Antonija ; Galić, Nada ; Marović, Danijela ; Gavic, Lidia ; Klarić, Eva ; Pejda, Slavica ; Ugrin, Klara ; Željezić, Davor

Izvornik
American journal of dentistry (0894-8275) 29 (2016), 4; 219-222

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
genotoxic effects ; cytotoxic effects ; dental composite materials ; micronucleus assay ; buccal mucosa cells

Sažetak
Purpose: To evaluate the possible geno/cytotoxic effects of dental composite materials by assessing the frequency of micronuclei formation and other nuclear abnormalities in the exfoliated buccal epithelium. Methods: Swabs were taken from the buccal mucosa among 85 young healthy subjects. All participants had healthy dentition or dentition restored only with composite materials. Genotoxicity and cytotoxicity was assessed by micronucleus assay. Results: The results indicated no significant difference in number of oral mucosa cells with micronuclei in subjects with different numbers of composite restored tooth surfaces (P=0476). Also, the number of restored surfaces had no effect on nuclear alterations closely related to cytotoxicity, such as karyolysis (P=0.572), karyorrehexis (P=0.573) and picnosis (P=0.765).

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina

POVEZANOST RADA