Naslov
Eosinophilic erythema annulare

Autori
Bartolić, Lucija ; Bradamante, Mirna ; Ljubojević Hadžavdić, Suzana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Skup
13th Europena Academy of Dermatology and Venereology Spring Symposium

Mjesto i datum
Atena, Grčka, 19.02.2016. - 22.02.2016

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
eosinophilic erythema annulare; Wells syndrome; antimalarials

Sažetak
Eosinophilic annular erythema (EAE) belongs to a group of figurate erythemas with a prominent tissue eosinophilia (there are only few case reports described in the literature), and is characterized clinically by the appearance of polycyclic lesions and annular plaques. We report a case of a 59 year old male patient who presented with one month history of itchy, polycyclic and annular lesions localized on the trunk, gluteal region and extremities. There was no medical history of drug intake. Extensive laboratory work up including serological infectious disease testing was done and it was within normal range. Skin biopsy showed a dense perivascular lymphocytic infiltrate with abundant eosinophils interstitially and within the subcutaneous fat. The aforementioned histological characteristics were compatible with the diagnosis of Erythema annulare centrifugum. High potency local steroids along with antihistamines were prescribed but without adequate therapeutic result. The patient was then given orally 40mg of prednisone but relapsed soon after the discontinuation of the treatment. Chloroquine was started in dose of 4mg per kg daily for 10 days, then 250 mg daily for 10 months, resulting in a complete clearance of all the lesions. The patient is well and disease free for 15 months now. According to some authors EAE is a clinical subtype of Wells syndrome presenting with an annular or figurate pattern. The etiology of EAE is still unknown and further reports may permit a better understanding of the prompt response to antimalarials.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA