Pregled bibliografske jedinice broj: 814698
Pulled Polymer Loops as a Model for the Alignment of Meiotic Chromosomes
Pulled Polymer Loops as a Model for the Alignment of Meiotic Chromosomes // Physical Review Letters, 115 (2015), 208102-1 doi:10.1103/PhysRevLett.115.208102 (međunarodna recenzija, članak, znanstveni)
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Naslov
Pulled Polymer Loops as a Model for the Alignment of Meiotic Chromosomes
Autori
Lin, Yen Ting ; Frömberg, Daniela ; Huang, Wenwen ; Delivani, Petrina ; Chacón, Mariola ; Tolić, Iva M. ; Jülicher, Frank ; Zaburdaev, Vasily
Izvornik
Physical Review Letters (0031-9007) 115
(2015);
208102-1
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
DNA recombination ; chromosome folding
Sažetak
During recombination, the DNA of parents exchange their genetic information to give rise to a genetically unique offspring. For recombination to occur, homologous chromosomes need to find each other and align with high precision. Fission yeast solves this problem by folding chromosomes in loops and pulling them through the viscous nucleoplasm. We propose a theory of pulled polymer loops to quantify the effect of drag forces on the alignment of chromosomes. We introduce an external force field to the concept of a Brownian bridge and thus solve for the statistics of loop configurations in space.
Izvorni jezik
Engleski
Znanstvena područja
Fizika, Biologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
- Nature Index
