Pregled bibliografske jedinice broj: 813361
Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report
Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report // Applied immunohistochemistry & molecular morphology, 24 (2016), 10; e89-e93 doi:10.1097/PAI.0000000000000361 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 813361 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Rapid fatal acute peripheral T-cell lymphoma
associated with IgG plasma cell leukemia and IgA
hypergammaglobulinemia : case report
Autori
Jonjić, Nives ; Seili-Bekafigo, Irena ; Fučkar- Čupić, Dora ; Lučin, Ksenija ; Duletić- Načinović, Antica ; Valković, Toni
Izvornik
Applied immunohistochemistry & molecular morphology (1541-2016) 24
(2016), 10;
E89-e93
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Leukemia ; plasma cell ; Lymphoma ; T cell ; Hypergammaglobulinemia
Sažetak
Simultaneous occurrence of T-cell and B-cell neoplasms is rare and etiologic relationships between these two malignancies are poorly understood. We describe a case of 66-year-old woman who was admitted to the hospital because of fever, hemoptysis, lymphadenopathy, and skin rash. Enlarged lymph nodes in the axillary, pectoral, paratracheal and periportal regions, as well as slight hepato- and splenomegaly were confirmed. Peripheral blood smear revealed rouleaux formation and numerous circulating plasma cells, with plasmacytoid lymphocytes. Immunofixation- electrophoresis detected a monoclonal band defined as IgG-lambda light chains with broad band polyclonal IgA. The patient died from abrupt splenic rupture before diagnostic work-up was finished. Postmortem examination revealed infiltration of atypical lymphoid cells exhibiting high proliferative activity admixed with typical and atypical plasma cells in several organs. Thus plasma cell leukemia (IgG-lambda) as a rare and aggressive variant of plasma cell myeloma in present case was associated with aggressive peripheral T cell lymphoma and polyclonal (IgA) plasmacytosis.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
MZOS-062-1081872-0091 - Angiogeneza u agresivnih ne-Hodgkinovih limfoma (Duletić-Načinović, Antica, MZOS ) ( CroRIS)
061-0620095-0082
061-0620095-0079
061-0620095-0078
Ustanove:
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka,
Fakultet zdravstvenih studija u Rijeci
Profili:
Antica Duletić-Načinović
(autor)
Dora Fučkar Čupić
(autor)
Toni Valković
(autor)
Irena Seili-Bekafigo
(autor)
Ksenija Jurinović
(autor)
Nives Jonjić
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE