Naslov
Vitamin D deficiency in children entering puberty, accidental or reality?

Autori
Miškić, Blaženka ; Knežević Praveček, Marijana ; Ćosić, Vesna

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
3rd Middle East & Africa Osteoporosis Meeting "IOF Regionals" : abstracts ; u: Osteoporosis International 26 (2015)( S2) ; Poster Presentation Abstracts 439–486 / - , 2015, S455-S456

Skup
Middle East & Africa Osteoporosis Meeting "IOF Regionals" (3 ; 2015)

Mjesto i datum
Abu Dhabi, Ujedinjeni Arapski Emirati, 05.12.2015. - 07.12.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
vitamin D; deficiency; children; puberty

Sažetak
In the study which investigated the association of selected genetic polymorphisms and BMD in boys reaching puberty, we observed influence of nutrition and behaviour patterns on ultrasounds bone mineral parameters too. We analysed all ultrasound parameters of calcanues with antrophometrics, biochemics and hormonal state at 168 boys between 11 and 13 years residing in Slavonski Brod, Croatia. Quantitative ultrasound measurements were undertaken with Sahara device (Hologic). We estimated dietary habits and other possible behavioural patterns associated with BMD: TV watching, use of computer, sun exposure/summer/ winter/hours per week, fizzy drinks/dl per day). Significant low levels of serum concentration of vitamin 25(0H)D3 (28.6 nmol/l) was found. The same did not show any statistical association with the ultrasound parameters. Children who took 850 mg of calcium per day had better parameters of BMD. We found that 34 % boys take 5 dl of fizzed drinks daily, 48 % ingest daily 600 mg of calcium and 63 % sits 4 h during computer use. Their physical activity is extremely low (10 % go out about 30–60 min 2x per week) ; as a sun exposition too (about 1 h during summer at 23 % ; on winter about 15 min at 15 %). An alarming fact is that the serum concentration of vitamin D3 that was found was significantly below normal. Blood analysis was done in mid-June after a long sunny period. 63 % of the children spend most of his free time in front of TV or computer. Most children consumed foods low in vitamin D and they are generally less active. Low serum vitamin D had no effect on bone metabolism? The question is whether the observed children achieved some extraskeletal effect of vitamin D due to this finding. We think it is necessary to consider the status of vitamin D3 in the pediatric population. It is well known the association of vitamin D levels with the development allergic or other autoimmune diseases. The results point out the possible need supplementation with vitamin D through longer period of adolescency.(1, 2, 3, 4) References: 1. Baeke F et al., Curr Opin Pharmacol 2010 Aug ; 10:482. 2. Gindee AA et al., Arch Intern Med 2009 ; 169:626. 3. Miškić B. Ovisnost ultrazvučnih parametara petne kosti u dječjoj dobi o genskim polimorfizmima (disertacija). Zagreb, Hrvatska: Medicinski fakultet Sveučilišta u Zagrebu ; 2010. str. 124. 4. Hewison M, Endocrinol Metab Clin North Am 2010 Jun ; 39:365.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Napomena
DOI: 10.1007/s00198-015-3361-1

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