Pregled bibliografske jedinice broj: 788760
Utjecaj glukoze i adipokina na porođajnu težinu kod trudnica sa šećernom bolesti tipa 1
Utjecaj glukoze i adipokina na porođajnu težinu kod trudnica sa šećernom bolesti tipa 1 // Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, 23 (2014), 4; 116-120 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 788760 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Utjecaj glukoze i adipokina na porođajnu težinu kod trudnica sa šećernom bolesti tipa 1
(The relation of glucose and adipokines to birthweight in type 1 diabetic pregnancy)
Autori
Berberović, Edina ; Ivanišević, Marina ; Horvatiček, Marina ; Kralik-Oguić, Saša ; Đelmiš, Josip.
Izvornik
Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics (1330-0091) 23
(2014), 4;
116-120
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Adiponectin; Birthweight; Leptin; Pregnancy; Type 1 diabetes
Sažetak
Aims. The aim of this study was to relate the levels of glucose, insulin, C-peptide, leptin and adiponectin in the maternal and umbilical vein serum to the birth weight in T1DM and healthy pregnancies. Methods. The study included 120 pregnant women divided into 4 groups: 30 suffering from type 1 diabetic pregnancy (T1DM) who gave birth to eutrophic and 30 who gave birth to macrosomic infants ; 30 from Control group (CTRL) who gave birth to eutrophic and 30 who gave birth to macrosomic infants. Serum insulin, C-peptide, leptin and adiponectin levels were quantified by ELISA. Results. Fetal macrosomia is associated with higher level of leptin in the fetal serum in both groups (T1DM: p=0.049 ; CTRL: p=0.031). Fetal levels of glucose and insulin have an influence on birth weight in the Control group (glucose: p=0.002 ; insulin: p=0.015). Adiponectin levels are higher in the maternal (p=0.001) and fetal serum (p<0.001) in eutrophic newborns of healthy pregnant women compared to the macrosomic newborns. Conclusion. The fetal growth is a complex process. Our results confirmed the relation between leptin and insulin levels and birth weight. They also suggest that adiponectin may be involved in the fetal growth.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
108-1080401-0385 - Dijabetes i metabolički sindrom nakon prethodnog gestacijskog dijabetesa (Ivanišević, Marina, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb
Profili:
Marina Horvatiček
(autor)
Edina Berberović
(autor)
SAŠA KRALIK OGUIĆ
(autor)
Marina Ivanišević
(autor)
Josip Đelmiš
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
Uključenost u ostale bibliografske baze podataka::
- EMBASE (Excerpta Medica)
- SCOPUS