Naslov
Maternal metal exposure and risk for child’s health

Autori
Piasek, Martina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts XI ISTERH Conference Recent Advances in Trace Element Research in Health and Disease ; u: Journal of Trace Elements in Medicine and Biology 32 (2015) (S) / - : Elsevier, 2015

Skup
XI ISTERH Conference Recent Advances in Trace Element Research in Health and Disease

Mjesto i datum
Srebreno, Hrvatska, 18.10.2015. - 22.10.2015

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cadmium; lead; mercury; perinatal exposure

Sažetak
Childbearing age is a vulnerable physiologic period for toxic metal effects due to common nutrient deficiencies and consecutive increased intake of both essential and toxic elements. During pregnancy, a major redistribution of elements occurs in the maternal body including accumulated toxic metals, which can easily pass through (Pb, MeHg and Hg-0) or are mostly accrued in the placenta (Cd and Hg++). In our research on healthy postpartum women in continental and coastal Croatia, we confirmed that, beside food as a source of metal exposure, tobacco smoke was the main source of Cd and Pb exposure in cigarette smokers. When comparing Cd levels in the maternal blood and placenta of nonsmokers, we identified regional differences of metal exposure, which was attributed to different dietary habits and geochemical characteristics of the soil. Our research in humans and laboratory rats has shown that toxic metals interact with micronutrients (Fe, Zn, Cu and Se) in the maternal body and during transplacental passage to the fetus. Due to the tendency of toxic metals to accumulate in internal organs during lifetime, their perinatal exposure and effects contributes to the total individual exposome and general burden of disease.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA