Naslov
Distribution of trace elements in whole blood, serum and urine of men with testicular cancer

Autori
Živković, Tanja ; Tariba, Blanka ; Gamulin, Marija ; Pizent, Alica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Journal of Trace Elements in Medicine and Biology, Abstracts XI. ISTERH Conference, Recent Advances in Trace Element Research in Health and Disease / Jurasović, Jasna ; Aschner, Michael - : Elsevier, 2015, 41-41

Skup
XI. ISTERH Conference, A joint conference with Nordic Trace Element Society (NTES) and Croatian Society for Biochemistry and Molecular Biology

Mjesto i datum
Dubrovnik, Hrvatska, 18.10.2015. - 22.10.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
essential elements; toxic elements; testicular cancer

Sažetak
The imbalance between toxic and essential elements in the organism can lead to increased sensitivity and contribute to the development of malignant disease. Concentration of selected trace elements was measured in whole blood, serum and urine of 99 subjects with newly diagnosed testicular cancer (TC) and 55 control subjects. We found significantly higher concentration of Fe and Pb in whole blood and serum, and As in serum of TC patients. Concentration of Na, Mg, Ca, Cu and Se was significantly lower in serum of TC patients. However, when measured in whole blood, concentration of Na, Mg, Ca and Cu was higher in TC patients than in control group. In urine of TC patients, we found significantly lower concentrations of Na and Cr, and higher concentration of Mn, Fe and Zn compared to control subjects. Taking into account the potential role of measured elements in the ethiopathogenesis of cancer, observed element redistribution may represent a risk factor for the testicular cancer development and/or progress.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA