Pregled bibliografske jedinice broj: 780770
The Isolation and Synthesis of Neodolastane Diterpenoids
The Isolation and Synthesis of Neodolastane Diterpenoids // Natural product reports, 32 (2015), 230-255 (međunarodna recenzija, članak, znanstveni)
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Naslov
The Isolation and Synthesis of Neodolastane Diterpenoids
Autori
Markovic, Dean ; Kolympadi, M. ; Deguin, B. ; Poree, F.-H. ; Turks, M.
Izvornik
Natural product reports (0265-0568) 32
(2015);
230-255
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
neodolastanes ; isolation ; synthesis ; biological activities
Sažetak
The neodolastane diterpenoids comprise a group of 44 compounds including guanacastepenes, heptemerones, plicatilisins, radianspenes, 2, 15-epoxy-5, 13-dihydroxyneodolast-3-en-14-one and sphaerostanol. These fungal and marine natural products are characterized by a tricyclic neodolastane skeleton that consists of fused five-, seven- and six-membered rings. Their reported antibiotic activities against antibiotic-resistant bacteria together with strong antifungal and anticancer activities and their novel structures render these compounds interesting synthetic targets. The aim of this account is to summarise the progress in the isolation, characterisation and synthesis of these diterpenoids as well as to review their biogenetic origins and diverse biological activities since their discovery in 2000.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
