Naslov
Leuconostoc sp. Meningitis in a Patient Treated with Rituximab for Mantle Cell Lymphoma.

Autori
Holik, Hrvoje ; Coha, Božena ; Šiško, Marijan ; Tomić- Paradžik, Maja

Izvornik
Turkish journal of hematology (1300-7777) 32 (2015), 3; 271-274

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Rituximab; Leuconostoc; Purulent meninigitis; Mantle cell lymphoma; R-CHOP

Sažetak
We present a 64-year-old man who was treated with R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone) chemoimmunotherapy for mantle cell lymphoma and developed purulent meningitis, probably caused by Leuconostoc sp. The patient had severe hypogammaglobulinemia, which is a possible complication of rituximab therapy. To our knowledge and after reviewing the available medical literature, this is the first described case of purulent meningitis caused by Leuconostoc sp. in a patient with mantle cell lymphoma that appeared after treatment with the R-CHOP protocol. The diagnosis of purulent meningitis was based on clinical, laboratory and cytological cerebrospinal fluid findings, in addition to blood culture results in which we isolated Leuconostoc sp. The patient was treated with meropenem with full recovery.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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