Naslov
Regional differences in sensitization to Ambrosia in Croatian children

Autori
Banić, Ivana ; Večenaj Ana, Miletić-Gospić Adrijana, Perica Marija ; Živković Jelena ; Plavec Davor , Cvitković Ante ; Peternel Renata ; Periš Nenad ; Turkalj, Mirjana.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
ERS International Congress 2014

Mjesto i datum
München, Njemačka, 06.09.2014. - 10.09.2014

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
ambrosia ; children ; Atopica

Sažetak
FP7 project ATOPICA (Atopic diseases in changing climate, land use and air quality) supported by EU Grant agreement NO: CP 282687 explores the combined pan-European impact of changes in climate, land use and air pollution on allergen pollen-induced diseases. To determine the prevalence and future incidence in allergy to Ambrosia in children from different exposure sites. Cohort of 3590 children, aged 4-10 years, was recruited from 3 regions of Croatia differing in Ambrosia pollen concentrations: Slavonia with the highest, Zagreb area with middle and Dalmatia with the lowest. Each participant underwent skin prick test (SPT) to the standard set of aeroallergens. Pollen concentrations and air quality data were gathered from authorized institutions. A total of 369 children were sensitized to Ambrosia pollen. Prevalence of Ambrosia sensitization was 14.84 % in Zagreb area, 14.26 % in Slavonia and 1.52 % in Dalmatia. Analysis of sensitization in two age groups (4-6 and 7-10 years) reveals higher prevalence of Ambrosia, birch and D. pteronyssinus sensitization as well as double sensitization (birch and Ambrosia) in older age group for all 3 regions. Sensitization to above allergens was more prevalent in male participants. After two pollen seasons of follow- up, de novo sensitized children were recorded: 2.88% in Zagreb area, 2, 73% in Slavonia and 0, 00% in Dalmatia. De novo sensitization was more prevalent in older age group. Region of Slavonia measures highest Ambrosia pollen concentrations and also most de novo sensitized children, which leads to assumption that de novo sensitization rates are primary correlated to exposure levels to Ambrosia pollen.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA