Naslov
Treatment of chronic constipation with lactulose syrup: results of a double-blind study

Autori
Wesselius-De Casparis, A. ; Braadbaart, S. ; v.d. Bergh-Bohlken, G. E. ; Mimica, Milorad

Izvornik
The Journal of The British Society of Gastroenterology-Gut (0017-5749) 9 (1968); 84-86

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
constipation; chronic; treatment; lactulose; syrup; study; double-blind

Sažetak
The effect of lactulose has been studied in a double-blind trial conducted in three different centres. One hundred and three regular laxative users were included in these trials. It appeared that approximately half of them (51) did not need a laxative at all, because they had a regular defaecation in the post-treatment period in which ali laxatives were withheld. In these 51 patients there was no significant difference between the effect of lactulose and glucose. In 52 truly constipated patients the effect of lactulose could be measured. The success rate for lactulose was 80%, for the placebo 33%. The difference in success rate is highly significant (P<001).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA