Naslov
Structural changes in the rat placenta during the last third of gestation discovered by stereology

Autori
Šerman, Ljiljana ; Žunić, Iris ; Vrsaljko, Nina ; Grbeša, Đurđica ; Gjurčević, Emil ; Matašin, Željka ; Nikuševa Martić, Tamara ; Bulić-Jakuš, Floriana ; Tlak Gajger, Ivana ; Šerman, Alan

Izvornik
Bosnian journal of basic medical sciences (1512-8601) 15 (2015), 1; 21-25

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
stereology; placenta; trophoblast giant cells; glycogenic cells

Sažetak
Structural changes in the rat placenta during the last third of gestation were for the first time assessed by stereology. Fischer female rats were euthanized on the 16th or 19th day of gestation, and 35 placentas were collected. Three randomly selected placentas from each group were stereologically analyzed for the absolute volume. The proportion of the glycogenic cells and the trophoblast giant cells (TGC) in the basal part of the placenta was calculated using volume density. The absolute volume of the rat placenta on the 16th day of gestation was determined as 0.0638 cm3. The labyrinth comprised 0.0274 cm3, the basal plate 0.0271 cm3 and the decidua 0.0093 cm3. On the 19th day of gestation, the absolute volume of the placenta was 0.1627 cm3, the labyrinth occupied 0.0922 cm3, the basal plate 0.0596 cm3 and the decidua 0.0109 cm3. The volume density of trophoblast giant cells was 0.174 cm0 on the 16th and 0.107 cm0 on the 19th day of gestation. The glycogenic cells comprised 0.379 percentage of the basal plate on the 16th and 0.236 on the 19th day of gestation. We conclude that the absolute volume of the whole placenta and the labyrinth has increased from 16th to the 19th day of gestation. In contrast, the volume density of glycogenic cells and trophoblast giant cells was higher on the 16th than on the 19th day of gestation, probably due to the intensive trophoblast invasion during that time.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Veterinarska medicina

POVEZANOST RADA