Naslov
Control of canine leptospirosis in Croatia – should we adjust our vaccination strategies?

Autori
Štritof Majetić, Zrinka ; Habuš, Josipa ; Milas, Zoran ; Mojčec Perko, Vesna ; Starešina, Vilim ; Barbić, Ljubo ; Perharić, Matko ; Stevanović, Vladimir ; Martinković, Krešimir ; Turk, Nenad

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of abstract of the 5th International Congress "Veterinary Science and Profession" / - Zagreb, 2013, 59-59

Skup
5th International Congress "Veterinary Science and Profession"

Mjesto i datum
Zagreb, Hrvatska, 03.10.2013. - 04.10.2013

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
dogs; leptospirosis; vaccination

Sažetak
Canine leptospirosis is a well known bacterial zoonosis with worldwide distribution. Infection of dogs results in illness of varying severity, depending on the virulence of the infecting strain and host immune response. During the last thirty years, a bivalent vaccine containing the bacterins of serovars Canicola and Icterohaemorrhagiae has been widely used in the prevention of the disease, resulting in a decline in its prevalence. However, many countries have receantly noted the increase in number of canine leptospirosis cases. Due to the diversity of agglutinins on the outer membrane, protection provided by the current vaccines is restricted only to the serogroups used in their production. Consequently, the observed reemergence was associated with changes in the infecting serovars and leptospires from other serogroups Grippotyphosa, Pomona, Sejroe, Australis have been confirmed as causative agents. The aim of this study was to determine the prevalence of presumptive infective serovars in dogs in Croatia. Serum samples from 151 dogs were submitted to the Laboratory for Leptospires, Faculty of Veterinary Medicine, University of Zagreb, during a period of four years (January 2006 to September 2010). The majority of samples originated from dogs with some form of clinical disease, mostly hepato-renal lesions. A microscopic agglutination test (MAT) against 12 Leptospira serovars was performed following standard procedure and 57 (37.7%) seropositive sera were detected. The most prevalent presumed infective serovars, in decreasing order, were: Pomona, Grippotyphosa, Icterohaemorrhagiae, Australis, Saxkoebing and Hardjo. Results showed that most infections were caused by serovars not covered by the most commonly used vaccines, which raises questions concerning its efficacy in preventing leptospirosis in dogs.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA