Naslov
Antibacterial activity of copper-containing clinoptilolite/ PVC composites toward clinical isolate of Acinetobacter baumannii

Autori
Milenković, Jelena ; Hrenović, Jasna ; Goić-Barišić, Ivana ; Tomić, Miloš ; Rajić, Nevenka

Izvornik
Journal of the Serbian Chemical Society (0352-5139) 80 (2015), 6; 819-826

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Natural zeolite; multidrug resistance; polymers; poly(vinyl chloride); amino acids.

Sažetak
The multidrug resistant bacteria Acinetobacter baumannii cause serious hospital infections. Commercial poly(vinyl chloride) (PVC) used for endotracheal tubes was modified in order to obtain the composite with antibacterial effect towards clinical isolate of A. baumannii ST145. The composites were prepared by addition of different amounts of copper-containing zeolite tuff (CuZ) and by successive impregnation with D-Tyrosine (D-Tyr) solution. The composites which were obtained by addition of CuZ (CuZ-PVC) only did not exhibit antibacterial effect. The impregnation of the CuZ-PVC by D-Tyr resulted in an antibacterial effect which is explained by a synergistic effect of CuZ and D-Tyr. Rheological tests confirmed that the modification of PVC by CuZ does not affect its processability and reformability.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

POVEZANOST RADA