Molecular and cellular approach in the study of antioxidant/prooxidant properties of Micromeria croatica (Pers.) Schott

Šamec, Dunja; Gruz, Jiri; Durgo, Ksenija; Kremer, Dario; Kosalec, Ivan; Valek Žulj, Lidija; Martinez, Sanja; Salopek-Sondi, Branka; Piljac-Žegarac, Jasenka

doi:10.1080/14786419.2014.999334

Pregled bibliografske jedinice broj: 740518

Molecular and cellular approach in the study of antioxidant/prooxidant properties of Micromeria croatica (Pers.) Schott

Šamec, Dunja; Gruz, Jiri; Durgo, Ksenija; Kremer, Dario; Kosalec, Ivan; Valek Žulj, Lidija; Martinez, Sanja; Salopek-Sondi, Branka; Piljac-Žegarac, Jasenka

Molecular and cellular approach in the study of antioxidant/prooxidant properties of Micromeria croatica (Pers.) Schott // Natural product research, 29 (2015), 18; 1770-1774 doi:10.1080/14786419.2014.999334 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 740518 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Molecular and cellular approach in the study of antioxidant/prooxidant properties of Micromeria croatica (Pers.) Schott

Autori
Šamec, Dunja ; Gruz, Jiri ; Durgo, Ksenija ; Kremer, Dario ; Kosalec, Ivan ; Valek Žulj, Lidija ; Martinez, Sanja ; Salopek-Sondi, Branka ; Piljac-Žegarac, Jasenka

Izvornik
Natural product research (1478-6419) 29 (2015), 18; 1770-1774

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
antioxidant ; cytotoxicity ; Micromeria croatica (Pers.) Schott. ; polyphenols ; prooxidant

Sažetak
Phytochemical composition and antioxidant activity of three wild populations of endemic Illyric-Balcanic species Micromeria croatica (Pers.) Schott have been evaluated with respect to plant organ and growing location. Multivariate analysis (PCA) was performed to visualize (dis-)similarity among samples and identify correlations between phytochemical variables that explain the most variability. The tested leaf extract from locality Bačić kuk exhibited protective effects against ROS- induced damage of DNA and inhibition of lipid peroxidation, while it caused oxidative degradation of protein in the BSA assay at higher concentrations. This extract also exhibited cytotoxic activity and facilitated the formation of ROS in the HEp2 cell line, in a dose-dependent manner.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija

POVEZANOST RADA

Projekti:
058-0582261-2246 - Utjecaj mutagena i antimutagena na molekularne procese u stanici (Hrašćan, Reno, MZOS ) ( CroRIS)
098-0982913-2829 - Molekularna regulacija biljnog razvitka (Salopek-Sondi, Branka, MZOS ) ( CroRIS)
125-0822161-2982 - INHIBICIJA KOROZIJE PRIRODNIM SPOJEVIMA: OD MOLEKULSKIH MODELA DO PRIMJENE (Martinez, Sanja, MZOS ) ( CroRIS)
006-0000000-3178 - Mikromorfološka i kemotaksonomska istraživanja nekih vrsta porodice Lamiaceae (Kremer, Dario, MZOS ) ( CroRIS)

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Prehrambeno-biotehnološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb

Profili:

Lidija Valek Žulj (autor)