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Pregled bibliografske jedinice broj: 732480

Synthesis of Fenoprofen Prodrugs

Zovko, Marijana; Zorc, Branka; Jadrijević-Mladar Takač, Milena
Synthesis of Fenoprofen Prodrugs // Abstracts, 6th European Congress on Pharmaceutical Sciences, EUFEPS 2000, European Journal of Pharmaceutical Sciences, 11, Supplement 1 (2000)pp. S1-S135 (September 2000) / Linden, H. Hans (ur.).
Oxford: Elsevier, 2000. str. S119-S119 (poster, međunarodna recenzija, sažetak, znanstveni)

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Naslov
Synthesis of Fenoprofen Prodrugs

Autori
Zovko, Marijana ; Zorc, Branka ; Jadrijević-Mladar Takač, Milena

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts, 6th European Congress on Pharmaceutical Sciences, EUFEPS 2000, European Journal of Pharmaceutical Sciences, 11, Supplement 1 (2000)pp. S1-S135 (September 2000) / Linden, H. Hans - Oxford : Elsevier, 2000, S119-S119

Skup
6th European Congress of Pharmaceutical Sciences, EUFEPS 2000

Mjesto i datum
Budimpešta, Mađarska, 16.09.2000. - 19.09.2000

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Fenoprofen; Prodrug; amides; Stirene-maleic copolymer ( SMA)

Sažetak
Fenoprofen (1), a well known analgesic and anti-inflammatory agent was transformed to amide derivatives 4 and 5. Fenoprofen first reacted with 1-benzotriazole carboxylic acid chloride (2) to give benzotriazolide 3 which after aminolysis gave the corresponding amides 4a-i. One of them, 2-aminoethyl amide (4i) reacted with styrene-maleic copolymer (SMA) affording the polymer-drug conjugate 5. In compound 5 fenoprofen is covalently bound by amide linkage, through nontoxic ethylenediamine spacer. The synthesised compounds are potential fenoprofen prodrugs.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija



POVEZANOST RADA

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb

Profili:

Avatar Url Milena Jadrijević-Mladar Takač (autor)

www.sciencedirect.com www.journals.elsevier.com

Citiraj ovu publikaciju:

Zovko, Marijana; Zorc, Branka; Jadrijević-Mladar Takač, Milena
Synthesis of Fenoprofen Prodrugs // Abstracts, 6th European Congress on Pharmaceutical Sciences, EUFEPS 2000, European Journal of Pharmaceutical Sciences, 11, Supplement 1 (2000)pp. S1-S135 (September 2000) / Linden, H. Hans (ur.).
Oxford: Elsevier, 2000. str. S119-S119 (poster, međunarodna recenzija, sažetak, znanstveni)
Zovko, M., Zorc, B. & Jadrijević-Mladar Takač, M. (2000) Synthesis of Fenoprofen Prodrugs. U: Linden, H. (ur.)Abstracts, 6th European Congress on Pharmaceutical Sciences, EUFEPS 2000, European Journal of Pharmaceutical Sciences, 11, Supplement 1 (2000)pp. S1-S135 (September 2000).
@article{article, author = {Zovko, Marijana and Zorc, Branka and Jadrijevi\'{c}-Mladar Taka\v{c}, Milena}, editor = {Linden, H.}, year = {2000}, pages = {S119-S119}, keywords = {Fenoprofen, Prodrug, amides, Stirene-maleic copolymer ( SMA)}, title = {Synthesis of Fenoprofen Prodrugs}, keyword = {Fenoprofen, Prodrug, amides, Stirene-maleic copolymer ( SMA)}, publisher = {Elsevier}, publisherplace = {Budimpe\v{s}ta, Ma\djarska} }
@article{article, author = {Zovko, Marijana and Zorc, Branka and Jadrijevi\'{c}-Mladar Taka\v{c}, Milena}, editor = {Linden, H.}, year = {2000}, pages = {S119-S119}, keywords = {Fenoprofen, Prodrug, amides, Stirene-maleic copolymer ( SMA)}, title = {Synthesis of Fenoprofen Prodrugs}, keyword = {Fenoprofen, Prodrug, amides, Stirene-maleic copolymer ( SMA)}, publisher = {Elsevier}, publisherplace = {Budimpe\v{s}ta, Ma\djarska} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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