Naslov
Surgical management of genital ambiguity

Autori
Batinica, Stipe ; Bradić, Ivan ; Luetić, Tomislav ; Antabak, Anko ; Župančić, Božidar ;

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
1st European congress of pediatric surgery. Abstract book. / - , 1995

Skup
1st European congress of pediatric surgery

Mjesto i datum
Graz, Austrija, 04.05.1995. - 06.05.1995

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
ambiguous genitalia; surgical treatment

Sažetak
Gender assignment in a child with ambiguous genitalia often is difficult and requires a full understanding of all factors involved, including chromosomal sex, anatomy of internal and external genital structures, gonadal function, predilection of gonads for malignancy, potential fertility and parental atitudes. These patients represent four major etiologic groups: adrenogenital syndrome, male pseudohermaphroditism, mixed gonadal dysgenesis and true hermaphroditism. Evaluation of a newborn with ambiguous genitalia should include a careful family history, physical examination and karyotype.On physical examination we look for a) bifid scrotum, b)labial rugae, c)hypospadias, d) chorde, e) gonads above or below the inguinal ring, f)palpation of an epididymis on the gonad, and g)a midline uterus during the rectal examination. Always are indicated to contrast studies of the urogenital system what also consist retrograde genitogram, pelvic ultrasound examination, then do biochemical evaluation and endoscopy studies.In patients with mixed gonadal dysgenesis, male pseudohermaphroditism and true hermaphroditism exploratory laparotomy and extraction of gonads is done first. The essential components of perineal reconstruction in infants to b e raised as females are 1( clitoral resection with preservation of glans, 2) flap vaginoplasty and 3)labioscrotal reduction. Till now , we have done feminizing genitoplasty reconstruction in 47 infants and children with ambiguous genitalia. These included 20 patients with adrenogenital syndrome or female pseudohermaphroditism, 16 with mixed gonadal dysgenesis, 11 male pseudohermaphroditism and one true hermaphroditism.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA