Naslov
Biological activity of extracts from selected Asteraceae plant species

Autori
Carev, Ivana ; Ferhatović, Lejla ; Politeo, Olivera ; Burčul, Franko ; Jukić, Mila ; Miloš, Mladen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
13^th Ružička days TODAY SCIENCE – TOMORROW INDUSTRY, Book of Abstracts / Šubarić, Drago - Osijek : Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2010, 102-102

ISBN
978-953-6894-40-6

Skup
13^th Ružička days TODAY SCIENCE – TOMORROW INDUSTRY

Mjesto i datum
Osijek, Hrvatska, 16.09.2010. - 17.09.2010

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Alzheimer; acetylcholinesterase; inhibition; antioxidation; <i>Centaurea ragusina</i>; <i>Inula verbascifolia</i>; <i>Pallenis spinosa</i>

Sažetak
Croatia flora is rich with plant species from Asteraceae familiy. Some of these species are well known medicinal plants, widely used in ethnomedicine. Since the substances used in treatment of some diseases are potentially harmful for human health, it is challenge to find active substances of natural origin like medicinal plants. Alzheimer disease (AD) is an incurable form of dementia which causes severe cognitive dysfunctions. AD is manifested as reduction of neurotransmitter acetylcholine inside the cholinergic system, hence the inhibition of acetylcholinesterase (AChE), enzyme that hydrolyses acetylcholine, has an important role in AD treatment. It is also considered that oxidative stress could be a trigger for AD development ; hence the research of AChE inhibitors is accompanied by assessment of their antioxidative activity. The aim of this work was to test AChE inhibitory activity as well as antioxidative activity of extracts from selected Asteraceae species: <i>Centaurea ragusina</i> L., <i>Inula verbascifolia</i> (Willd.) Hausskn and <i>Pallenis spinosa</i> (Cass.) Cass.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA