Naslov
Urosepsis in patients hospitalized at the University Hospital for Infectious Diseases "Dr Fran Mihaljevic" in Zagreb during 2009

Autori
Elvira Čeljuska-Tošev ; Arjana Tambić-Andrašević ; Suzana Bukovski-Simonoski

Izvornik
Infektološki glasnik (1331-2820) 30 (2010), 2; 59-68

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
urosepsa; čimbenici rizika; osjetljivost na antibiotike
(urosepsis; risk factors; antibiotic sensitivity)

Sažetak
Altogether 301 patients with urosepsis were hospitalized at the University Hospital for Infectious Diseases "Dr Fran Mihaljevic" in Zagreb during 2009, comprising a total of 47% patients with sepsis. These were mostly cases of secondary, community acquired sepsis, often a consequence of complicated and recurrent urinary tract infections (UTI). Mostly elderly patients (223 ; 74%) were hospitalized, older than 60 years of age, with some of the risk factors present in over 60% of cases. The disease occurred more frequently in women (68, 44%). Enterobacteria were isolated in 276 (62, 30%) samples, most commonly E.coli (41, 76%), K. pneumoniae (9, 54%) and P. mirabilis (8, 35%). Enterobacterial resistance to co- amoxiclav was 11, 96%, ceftriaxone 17, 75%, cefuroxime 20, 29%, ciprofloxacin 25, 72%, gentamicin 13, 04%, co-trimoxazole 37, 32% and nitrofurantoin 25%. The resistance of a single most common pathogen, E.coli, was within expected levels, to amoxicilin 58, 70%, co- trimoxazole 29, 19%, co-amoxiclav 4, 32% with intermediate susceptibility of 10, 27% and to ciprofloxacin 16, 22%. The therapy in the majority of patients was started as empirical, parenteral, and was continued according to antibiogram results, so that the most commonly administered drug was co-amoxiclav and II and III generation cephalosporins. The majority of urosepsis cases were classified as moderately severe sepsis in 74%, while septic shock was recorded in 18% of patients. In the majority of patients the outcome of treatment was favorable, so that 87% of patients were discharged from hospital as improved or cured, while 13% of the patients died.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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