Naslov
The impact of imipenem consumption on resistance rates

Autori
Schönwald, Slavko ; Baršić, Bruno

Izvornik
International Journal of Antimicrobial Agents (0924-8579) 17 (2001), Supplement 1;

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kongresno priopcenje, znanstveni

Sažetak
Imipenem consumption and resistance rates of Gram-negative pathogenes to imipenem were monitored in the period of 2 years. The monitoring was conducted in intensive care units in 10 hospitals. Imipenem consumption was expressed in Defined Daily Doses (DDD) and the resistance rate was monitored in all Gram-negative bacteria, especially in Pseudomonas aerugionsa. The results obrained in the period from 1998 to 2000 show no detecttable correlation between antibiotic consumption and resistance occurrence, meaning there was no direct impact of imipenem consumption on resistance manifestation. During imipenem administration a special attention was given to indications, dosage and treatment duration. Conclusion: If proper therapy is implemented, meaning correct treatment duration and dosage, resistance rates need not increase.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA