Naslov
Gorlin Goltz Syndrome and Stroke: Case Report.

Autori
Budinčević, Hrvoje ; Starčević, Katarina ; Bielen, Ivan ; Demarin, Vida

Izvornik
Acta dermatovenerologica Croatica (1330-027X) 22 (2014), 3; 209-212

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Gorlin-Goltz syndrome; stroke; PAI-1 gene polymorphism

Sažetak
We report on the case of a 32-years old male patient who was previously diagnosed with Gorlin- Goltz syndrome. The patient presented with sudden- onset right-sided hemiparesis, supranuclear facioparesis, and motor aphasia. He was treated with thrombolytic therapy, which successfully alleviated the symptoms. Subsequent radiologic work-up revealed anomalies in the vertebral arteries, a bifid rib, an ischemic lesion in the supply area of the left middle cerebral artery, and falx calcifications. Laboratory tests showed a 4G/4G polymorphism of the plasminogen activator inhibitor 1 (PAI-1) gene whose correlation with stroke is discussed in the article.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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