Pregled bibliografske jedinice broj: 719703
A cation-directed two-component cascade approach to enantioenriched pyrroloindolines
A cation-directed two-component cascade approach to enantioenriched pyrroloindolines // Chemical communications, 50 (2014), 88; 13585-13588 doi:10.1039/C4CC06683A (međunarodna recenzija, članak, znanstveni)
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Naslov
A cation-directed two-component cascade approach to enantioenriched pyrroloindolines
Autori
Wolstenhulme, Jamie R. ; Cavell, Alex ; Gredičak, Matija ; Driver, Russell W. ; Smith, Martin D.
Izvornik
Chemical communications (1359-7345) 50
(2014), 88;
13585-13588
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
organocatalysis; pyrroloindoline; phase-transfer catalysis; cascade reaction
Sažetak
A cascade approach to complex pyrroloindolines bearing all-carbon quaternary stereocentres has been developed. This two-component process uses a chiral ammonium salt to control diastereo- and enantioselectivity in the addition of isocyanides to functionalized alkenes to afford pyrroloindolines with up to three stereocentres. A mechanistic proposal involving intramolecular hydrogen bond activation of the isocyanide is described.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
