Naslov
Whole body microwawe exposure and peripheral blood of rats: a pilot study

Autori
Mataušić-Pišl, Mirjana ; Trošić, Ivančica ; Pišl, Zoran ; Radalj, Željko ;

Izvornik
Veterinarski arhiv (0372-5480) 70 (2000), 5; 279-287

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
microwave irradiation; Wistar rats; non-ionizing radiation; non-thermal effects; hematological parameters

Sažetak
This study was an attempt to determine biomarkers of non-ionizing, low-level microwave exposure in an animal model. It investigated the effects of continuous-wave radiation on peripheral blood in Wistar rats. The radiation frequency applied was 2450 MHz, while the average power density of the induced field was 10 mW/cm2. Forty 13-weeks-old male Wistar rats, of average body weight 350 g, were divided in groups G1 and G2. Group G2 comprised 20 animals, exposed to microwaves for 30 days (5 days a week, 2 hours a day), and group G1 comprised 20 unexposed controls. Peripheral blood samples were taken immediately after irradiation on the 1st, 8th, 16th and 30th day of the experiment. The total number of erythrocytes and leukocytes, as well as the differential leukocyte count, were investigated and compared. The results revealed an insignificant increased in the total erythrocytes count in microwave-exposed animals (p> 0.05) with respect to controls. Total leukocyte counts was consistently decreased in irradiated animals from eight day of irradiation (p< 0.05), while relative lymphocyte counts was significant decreased from day first. Slightly increase in the relative proportion of polymorphonuclear granulocytes was insignificant (p>0.05) in comparison to control. Our preliminary investigation suggests that microwave exposure may affect the hematological parameters of exposed animals, and call for further evaluation of specificity and biological significance of these biomarkers of exposure.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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