Naslov
Mice lacking trefoil family factor 3 gene present with reduced rate of monounsaturated fatty acids in the liver

Autori
Mihalj, Martina ; Bujak, Maro ; Tartaro Bujak, Ivana ; Tolušić Levak, Maja ; Mišković, Katarina ; Kopačin, Vjekoslav ; Mihaljević, Branka ; Drenjančević, Ines ; Baus-Lončar, Mirela

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
9. Annual Physiology summer meeting,

Mjesto i datum
London, Ujedinjeno Kraljevstvo, 30.06.2014. - 02.07.2014

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
liver ; TFF3 ; glucose ; lipid

Sažetak
The aim of this study was to determine the rate of monounsaturated fatty acids (MUFAs) in the liver of Tff3 knock-out mice, as well as the serum glucose and lipid content. We found that: Tff3 knock-out mice compared to WT mice have significantly lower amount of MUFAs in the liver Total serum levels of the cholesterol, triglycerides, HDL or LDL cholesterol did not differ between WT and TFF3 defcient mice. Postprandial glucose levels in Tff3 knock-out mice were higher than in controls but did not reach statistical significance. Microscopic analysis of the liver sections revealed normal tissue architecture (HE) and glycogen reserves (PAS staining).

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA