Pregled bibliografske jedinice broj: 702870
Varicella zoster virus DNA does not accumulate in infected human neurons
Varicella zoster virus DNA does not accumulate in infected human neurons // Virology, 1-3 (2014), 458-459 doi:10.1016/j.virol.2014.04.014 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 702870 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Varicella zoster virus DNA does not accumulate in infected human neurons
Autori
Baird, NL ; Bowlin, JL ; Yu, X ; Jonjić, Stipan ; Haas, J ; Cohrs, RJ ; Gilden, D.
Izvornik
Virology (0042-6822) 1-3
(2014);
458-459
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Human neurons; Tissue culture; VZV DNA
Sažetak
Varicella zoster virus (VZV) is an exclusively human neurotropic alphaherpesvirus. It is unclear why human neurons infected in vitro with VZV at low multiplicity of infection do not exhibit a cytopathic effect (CPE) even though all VZV genes are transcribed, VZV proteins from all kinetic classes are translated and minimal infectious virus is produced. Here, we show that the lack of VZV-induced CPE correlates with the low abundance of viral DNA
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
062-0621261-1263 - Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru (Jonjić, Stipan, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Rijeka
Profili:
Stipan Jonjić
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE