Naslov
HLA B-27 antigen and rheumatoid arthritis

Autori
Jajić, Zrinka ; jajić, INes ; Jajić, IVo.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts ILAR'93, u:Current Opinion in Rheumatology 1993 ; 20(suppl. 1):398. / - Barcelona, 1993, 398-398

Skup
ILAR'93

Mjesto i datum
Barcelona, Španjolska, 04.07.1993. - 09.07.1993

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
antigen HLA-B27; rheumatoid arthritis

Sažetak
The influence of HLA-B27 antigen on clinical, radiological and laboratory features of rheumatoid arthritis (RA) was studied. the group with B27 antigen comprised: 4 males and 20 females aged 28 do 71 and a group of patients free from B27 antigen consisted of 2 males and 21 females aged 26 to 69. RA patients possesing the B27 antigen did not differ regarding the age of the onset of disease, the distribution of affected joints during the follow-up (3-10 years), the development stages of the disease and the presence of rheumatoid factor when compared with B27 negative RA patients. The arthritis of the radiocarpal joints (p0.01) was significantly more often the first sign of the disease in patients with B27 antigen. In these patients low back pain and morning stiffness in the low back were twice as frequent as they were in patients not possessing the antigen. The clinical pattern of the affected spone was also found more frequently in B27 carriers (p0.05). B27 positive RA patients showed also the clinical pattern of sacroiliitis (SI) and x-ray SI (p0.01) significantly more often than the patients free from antigen. In addition, symetric arthritis of the peripheral joints was more often diagnosed in patients free from B27 antigen.

Izvorni jezik
Engleski

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