Naslov
Antibiotic resistance of gram-positive bacteria at the Sestre Milosrdnice University Hospital

Autori
Jajić Benčić, Ines ; Benčić, Ivan.

Izvornik
Acta clinica Croatica (0353-9466) 40 (2001); 15-19

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Gram positive bacteria; drug effects; drug resistance; microbial; bacterial infections; microbiology

Sažetak
The study was performed to provide current resistance data on gram-positive pathogens at the Sestre milosrdnice University Hospital in Zagreb. The organisms selected for monitoring of antimicrobial resistance to different antibiotics included Streptococcus pneumoniae, Streptococcus pyogenes, methicillin sensitive and resistant Staphylococcus aureus, and Enterococcus sp., isolated from different clinical specimens of hospitalized adults and children from various Hospital wards. The antibiotic sensitivity testing was performed by disk diffusion and E-test method. Resistance of Streptococcus pneumoniae to penicillin was found to be of great importance. It was quite common but moderate, so penicillin remained an appropriate choice in empirical therapy for presumed pneumococcal respiratory infections. Resistance of Streptococcus pyogenes to azithromycin was also quite significant, posing a question whether macrolides were an appropriate choice in empirical therapy for presumed Streptococcus pyogenes tonsillopharynitis. As many as 38% of Enterococcus sp. could not be treated by a by a coombination of penicillin or glycopeptide and gentamicin because of the high-level resistanace to gentamicin. Resistance to antibiotics in methicillin sensitive Staphylococcus aureus was not observed. Antibiotic resistance data on gram-positive pathogens influence the choice of local empirical therapy and allow for a more rational use of antibiotics at a hospital.

Izvorni jezik
Engleski

POVEZANOST RADA