Naslov
Complex disorder of neuronal migration in an infant with possible congenital cytomegaloviral infection

Autori
Mardešić, Duško ; Sučić Zvonko ; Papa, Jurica ; Senečić, Irena ; Sarnavka, Vladimir ; Škarpa, Drago

Izvornik
Acta medica Croatica (1330-0164) 50 (1996), 3; 151-155

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
neuronal migration disorder; agyria-pachygyria; lyssencephaly; infant; congenital cytomegaloviral infection

Sažetak
A ten months old girl was evaluated for developmental delay, increased muscle tone and seizures. CT and MRI revealed an uncommon combination of two different manifestations of neuronal migration disturbance: agyria/pachygyria and subcortical laminar heterotopia (double cortex syndrome). The possible pathogenesis of such a complex disorder could probably be established only by histologic examination of the brain. A positive serologic reaction to cytomegalovirus infection in the infant at the age of 11 months and in the mother suggested but did not prove the cytomegalovirus infection in early gestation as the cause of the disorder.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA