Naslov
Sensitization to house dust mites(HM) and storage mites (SM) in an adult population in Croatia

Autori
Kanceljak, Božica ; Macan, Jelena ; Buneta, Lucija ; Mlinarević, Vesna ; Pavelić, Ljubomir ; Milković-Kraus, Sanja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
The Annual Meeting of the European Academy of Alergology and Clinical Immunology, EAACI 97 / Kontou-Fili, K. ; Deliargyris, N. - Kopenhagen : European Academy of Allergology and Clinical Immunology, 1997, 61-62

Skup
The Annual Meeting of the European Academy of Alergology and Clinical Immunology, EAACI 97

Mjesto i datum
Rodos, Grčka, 01.06.1997. - 05.06.1997

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
allergy; house dust mites; storage mites; skin prick test; specific IgE; general population

Sažetak
Specific IgE (sIgE) and skin prick test (SPT) to HM: Dermatophagoides pteronyssinus (DP), Dermatophagoides farinae (DF) and SM: Lepidoglyphus destructor (LD), Tyrophagus putrescentiae (TP) were performed in a random sample of 67 men (40.6 ą 7.7 yrs) from the continental region of Croatia. SPT was performed with Epipharm-ALK allergens. An urtica D+d/2 3mm or greater was considered a positive skin reaction (PT+). sIgE was measured by immunoCAP technoloy UNI CAP (Pharmacia AB Diagnostics). Values <0.35 kUA/L were considered nonspecific (sIgEo) and values ł0.35 kUA/L increased (sIgE+). In relation to the level of sIgE skin reactivity was analysed as the prevalence of PT+ and mean D+d/2. The highest prevalence of sIgE+ was found to DP and DF (16/67=23.9%) and lower to LD (10/67=14.9%) and TP (15/67=22.3%). Among subjects with sIgE+ there were PT+ to DP and DF 10/16=62.5%, to LD 9/10=90% and to TP 13/15=93.3% ; among subjects with sIgEo PT+ to DP and DF 5/51=9.8%, to LD 9/57=15.8% and to TP 10/52=19.2%. Amon subjects with sIgE+ to DP there were sIgE+ to DF in 15/16=93.8%, to LD in 8/16=50% and to TP 12/16=75%, indicating cosensitization to SM in more than 50% of HM sensitized persons. Significant difference of mean D+d/2 in PT+ reaction between sIgEo and sIgE+ subjects was found only for LD (3.56 ą 0.68 ; 6.2 ą 2.8, P<0.02) and not for DF, DP and TP. Our results suggest that the level of sIgE to LD better discrimates skin reactivity than IgE to DP, DF and TP.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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