Pregled bibliografske jedinice broj: 683533
Acute graft versus host disease after orthotopic liver transplantation
Acute graft versus host disease after orthotopic liver transplantation // Journal of hematology & oncology, 5 (2012), 50-55 doi:10.1186/1756-8722-5-50 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 683533 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Acute graft versus host disease after orthotopic liver transplantation
Autori
Mandac Rogulj, Inga ; Deeg, Joachim ; Lee, Stephanie J.
Izvornik
Journal of hematology & oncology (1756-8722) 5
(2012);
50-55
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
acute graft versus host disease; orthotopic liver transplantation
Sažetak
Graft versus host disease (GVHD) is an uncommon complication after orthotopic liver transplantation (OLT) with an incidence of 0.1 – 2%, but an 80 – 100% mortality rate. Patients can present with skin rashes, diarrhea, and bone marrow aplasia between two to eight weeks after OLT. Diagnosis of GVHD is made based on clinical and histologic evidence, supported by chimerism studies showing donor HLA alleles in the recipient bone marrow or blood. Several therapeutic approaches have been used for the management of GVHD after OLT including increased immunosuppression, decreased immunosuppression, and cellular therapies. However, success rates have been low, and new approaches are needed.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
044-1081873-1281 - Hematološki poremećaji u bolesnika sa kardiomiopatijama (Planinc-Peraica, Ana, MZOS ) ( CroRIS)
Ustanove:
Klinička bolnica "Merkur",
Medicinski fakultet, Zagreb
Profili:
Inga Mandac Smoljanović
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
