Naslov
Treatment results of childrenhood acute lymphatic leukemia in Croatia using the ALL-BFM 90 protocol

Autori
Konja, Josip ; Femenić, Ranka ; Rajić, Ljubica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Meeting og the International BFM Study Group / Conter, Valentino ; Manganini, Carla - Groningen : BFM Study Group, 2000

Skup
11th annual Meeting og the International BFM Study Group

Mjesto i datum
Groningen, Nizozemska, 09.05.2000. - 11.05.2000

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
BFM protocol; leukaemia; children

Sažetak
Purpose: Children (86) with acute lymphatic leukaemia (ALL) were treated with protocol ALL-BFM 90 from 1st June 1992 to 1st June 1997. The results of treatment were analysed. Methods and results: The first complete remission was achieved in 86 (100%-33 day; in 71/83%-15 day). The first relapse occurred in 12 (14%) patients (9 hematologic relapse; 1 meningeal relapse, 2 hematologic and meningeal relapse). Afrer a median observation time of 32 months the overall probability for eventfree survival (p-EFS) is 81+/-2%. 14 patients (16%) died (12 during relapse and 2 for other reasons). At this time p-EFS for each strategic group is: 87+/-3% for SRG, 86+/-2% for MRG and 41+/-5% for HRG. Conclusion: These preliminary results indicate that for 85% of ALL patients risk-adapted intensive therapy provide a high chance for cure and the achieved results do not differ gratly from the results achived by other European Centres for the treatment of acute lymphatic leukaemia.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA