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Pregled bibliografske jedinice broj: 677712

Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production

Grausenburger, Reinhard; Bilić, Ivan; Boucheron, Nicole; Zupkovitz, Gordin; El-Housseiny, Lamia; Tschismarov, Roland; Zhang Yu; Rembold, Martina; Gaisberger, Martin; Hartl, Arnulf et al.
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production // Journal of immunology, 185 (2010), 6; 3489-3497 doi:10.4049/jimmunol.0903610 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 677712 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production

Autori
Grausenburger, Reinhard ; Bilić, Ivan ; Boucheron, Nicole ; Zupkovitz, Gordin ; El-Housseiny, Lamia ; Tschismarov, Roland ; Zhang Yu ; Rembold, Martina ; Gaisberger, Martin ; Hartl, Arnulf ; Epstein, Michelle ; Matthias, Patric ; Seiser, Christian ; Ellmeier, Wilfried

Izvornik
Journal of immunology (0022-1767) 185 (2010), 6; 3489-3497

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
T lymphocytes; development

Sažetak
Chromatin modifications, such as reversible histone acetylation, play a key role in the regulation of T cell development and function. However, the role of individual histone deacetylases (HDACs) in T cells is less well understood. In this article, we show by conditional gene targeting that T cell-specific loss of HDAC1 led to an increased inflammatory response in an in vivo allergic airway inflammation model.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA

Projekti:
098-0982913-2332 - Molekularne interakcije u diferencijaciji limfocita (Antica, Mariastefania, MZOS ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Ivan Bilić (autor)

Poveznice na cjeloviti tekst rada:

doi www.jimmunol.org

Citiraj ovu publikaciju:

Grausenburger, Reinhard; Bilić, Ivan; Boucheron, Nicole; Zupkovitz, Gordin; El-Housseiny, Lamia; Tschismarov, Roland; Zhang Yu; Rembold, Martina; Gaisberger, Martin; Hartl, Arnulf et al.
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production // Journal of immunology, 185 (2010), 6; 3489-3497 doi:10.4049/jimmunol.0903610 (međunarodna recenzija, članak, znanstveni)
Grausenburger, R., Bilić, I., Boucheron, N., Zupkovitz, G., El-Housseiny, L., Tschismarov, R., Zhang Yu, Rembold, M., Gaisberger, M. & Hartl, A. (2010) Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production. Journal of immunology, 185 (6), 3489-3497 doi:10.4049/jimmunol.0903610.
@article{article, author = {Grausenburger, Reinhard and Bili\'{c}, Ivan and Boucheron, Nicole and Zupkovitz, Gordin and El-Housseiny, Lamia and Tschismarov, Roland and Rembold, Martina and Gaisberger, Martin and Hartl, Arnulf and Epstein, Michelle and Matthias, Patric and Seiser, Christian and Ellmeier, Wilfried}, year = {2010}, pages = {3489-3497}, DOI = {10.4049/jimmunol.0903610}, keywords = {T lymphocytes, development}, journal = {Journal of immunology}, doi = {10.4049/jimmunol.0903610}, volume = {185}, number = {6}, issn = {0022-1767}, title = {Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production}, keyword = {T lymphocytes, development} }
@article{article, author = {Grausenburger, Reinhard and Bili\'{c}, Ivan and Boucheron, Nicole and Zupkovitz, Gordin and El-Housseiny, Lamia and Tschismarov, Roland and Rembold, Martina and Gaisberger, Martin and Hartl, Arnulf and Epstein, Michelle and Matthias, Patric and Seiser, Christian and Ellmeier, Wilfried}, year = {2010}, pages = {3489-3497}, DOI = {10.4049/jimmunol.0903610}, keywords = {T lymphocytes, development}, journal = {Journal of immunology}, doi = {10.4049/jimmunol.0903610}, volume = {185}, number = {6}, issn = {0022-1767}, title = {Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production}, keyword = {T lymphocytes, development} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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