Naslov
Selective advantage of S-layer surface proteins presence in Lactobacillus probiotic strains

Autori
Beganović, Jasna ; Uroić, Ksenija ; Leboš Pavunc, Andreja ; Kos, Blaženka ; Šušković, Jagoda

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
ANNUAL 2013/2014 OF THE CROATIAN ACADEMY OF ENGINEERING / - , 2013

Skup
The 2nd International Symposium "Vera Johanides" - Biotechnology in Croatia by 2020

Mjesto i datum
Zagreb, Hrvatska, 10.05.2013. - 11.05.2013

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
functionality; Lactobacillus; probiotic; S-layer surface proteins

Sažetak
Bacterial surface (S-) S-layers are macromolecular paracrystalline arrays covering cell envelope which are composed of identical protein or glycoprotein subunits. So far, among numerous lactic acid bacteria (LAB) species these proteins have been identified only between several Lactobacillus members. The S-layer proteins of Lactobacillus strains have specific features and their biological roles have not yet been fully elucidated. Although these surface proteins are yet to be characterised, several functional roles in Lactobacillus cells have been proposed. In fact, some probiotic properties of Lactobacillus bacteria, such as adhesion, pathogens exclusion and immunomodulation have been related with the occurrence of S-layers. Hence, in this manuscript the most recent studies together with the results obtained in PhD. Jagoda Šušković, Prof. research group, concerning S-layer protein characterisation are summarised. Especially the functional role of S-layer protein in important probiotic traits, adhesion to intestinal epithelial cells, immunomodulation activity and in competitive exclusion of pathogens by Lactobacillus strains, is discussed.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

POVEZANOST RADA