High infection rate of bank voles (Myodes glareolus) with Puumala virus is associated with a winter outbreak of haemorrhagic fever with renal syndrome in Croatia.

Tadin, Ante; Bjedov, Linda; Margaletić, Josip; Zibrat, Branka; Cvetko Krajinović, Lidija; Svoboda, Petra; Kurolt, Ivan Christian; Štritof Majetic, Zrinka; Turk, Nenad; Đaković Rode, Oktavija; Čivljak, Rok; Kuzman, Ilija; Markotić, Alemka

doi:10.1017/S095026881300321X

Pregled bibliografske jedinice broj: 674983

High infection rate of bank voles (Myodes glareolus) with Puumala virus is associated with a winter outbreak of haemorrhagic fever with renal syndrome in Croatia.

Tadin, Ante; Bjedov, Linda; Margaletić, Josip; Zibrat, Branka; Cvetko Krajinović, Lidija; Svoboda, Petra; Kurolt, Ivan Christian; Štritof Majetic, Zrinka; Turk, Nenad; Đaković Rode, Oktavija et al.

High infection rate of bank voles (Myodes glareolus) with Puumala virus is associated with a winter outbreak of haemorrhagic fever with renal syndrome in Croatia. // Epidemiology and infection, 142 (2014), 9; 1945-1951 doi:10.1017/S095026881300321X (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 674983 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
High infection rate of bank voles (Myodes glareolus) with Puumala virus is associated with a winter outbreak of haemorrhagic fever with renal syndrome in Croatia.

Autori
Tadin, Ante ; Bjedov, Linda ; Margaletić, Josip ; Zibrat, Branka ; Cvetko Krajinović, Lidija ; Svoboda, Petra ; Kurolt, Ivan Christian ; Štritof Majetic, Zrinka ; Turk, Nenad ; Đaković Rode, Oktavija ; Čivljak, Rok ; Kuzman, Ilija ; Markotić, Alemka

Izvornik
Epidemiology and infection (0950-2688) 142 (2014), 9; 1945-1951

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Hantaviruses ; Outbreaks ; Rodents

Sažetak
An outbreak of haemorrhagic fever with renal syndrome (HFRA) started on Medvednica mountain near Zagreb in January 2012. In order to detect the aetiological agent of the disease in small rodents and to make the link with the human outbreak, rodents were trapped at four different altitudes. Using nesed RT-PCR, Puumala virus (PUU) RNA was detected in 41/53 (77.4) bank voles (Myodes glareolus) and Dobrava virus (DOB) RNA was found in 6/61 (9.8) yellow-necked mice (Apodemus flavicollis). Sequence analysis of a 341-nucleotide region of the PUUV S segment, obtained from all i8nfected bank voles and five HFRS patients, showed 98.8-100% sequence similarity, indicating that the patients were probably exposed to PUU on Medvednioca mountain. A very large bank-vole population combined with an extremely high infection rate of PUUV was responsible for this unusual winter outbreak of HFRS in Croatia.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA

Projekti:
053-1430115-2116 - Molekularna epizootiologija i epidemiologija leptospiroze (Turk, Nenad, MZOS ) ( CroRIS)
068-1430115-2119 - Šumski ekosustavi kao prirodna žarišta hantavirusa i leptospira (Margaletić, Josip, MZOS ) ( CroRIS)
108-0000000-3491 - ISTRAŽIVANJE ETIOLOGIJE I PATOGENEZE PNEUMONIJA (Kuzman, Ilija, MZOS ) ( CroRIS)
143-1430115-0103 - Imunoreakcije na hantaviruse i leptospire (Markotić, Alemka, MZOS ) ( CroRIS)

Ustanove:
Veterinarski fakultet, Zagreb,
Fakultet šumarstva i drvne tehnologije,
Medicinski fakultet, Zagreb,
Klinika za infektivne bolesti "Dr Fran Mihaljević"

Profili:

Ivan-Christian Kurolt (autor)