Naslov
Renal cortical scintigraphy in children: estimation of differential function with MAG3 and DMSA

Autori
Smokvina, Aleksandar ; Grbac-Ivanković, Svjetlana ; Girotto, Neva

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Third European Symposium on Paediatric Nuclear Medicine / Paediatric Committee of the EANM - Lahti : Paediatric Committee of the EANM, 2000, Izdanje na CD-u

Skup
Third European Symposium on Paediatric Nuclear Medicine

Mjesto i datum
Girona, Španjolska, 12.05.2000. - 13.05.2000

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Renal cortical scintigraphy; MAG3; DMSA

Sažetak
Calculating the split renal function and its contribution to the global function on radionuclide static scintigraphy with DMSA is widely used in children population in evaluation of renal parenchyma. Dynamic tracer MAG3 is rarely used for this purpose. The aim of this study was to compare differential function obtained with DMSA and during parenchymal phase of dynamic study with MAG3. DMSA scintiscans of 55 children referred to our department (44 girls, 11 boys, mean age 8.3, range 1-15 years), were compared to the initial phase (first 60 - 120 sec) of the MAG3 study performed in the same patient . Conditions of detection were the same for both procedures (the same gamma camera, supine position with collimator underneath) and the time elapsed between two studies did not exceed three months. Regions of interest were manually drawn over each kidney on DMSA and MAG3 scintiscans, respectively. The results showed that in 93% of cases split renal function (ratio) calculated from both procedures showed variations smaller than 5%. Moreover, in more than two thirds (69%) of the cases split renal function differed less than 2%. From the results obtained we concluded that renal parenchymal uptake in children can be successfully measured during the initial phase of MAG3 study as well as with DMSA. The advantage of performing MAG3 study in evaluation of renal parenchyma as an initial nuclear medicine procedure is in a possibility to get more information (function, collecting system), and in the same time diminish radiation exposure. Only in minor proportion of children DMSA may still be necessary.

Izvorni jezik
Engleski

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