Naslov
Toxic epidermal necrolysis caused by flurazepam?

Autori
Lončar, Časlav ; Franić, Tomislav ; Bilušić, Marijo

Izvornik
Psychiatria Danubina (0353-5053) 17 (2005), 3-4; 236-239

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
Stevens-Johnson syndrome - toxic epidermal necrolysis - drug hypersensitivity -flurazepam

Sažetak
Stevens-Johnson syndrome and toxic epidermal necrolysis are rare, but severe cutaneous reactions. Beside cutaneous manifestations, the syndrome is characterised by constitutional sypmtoms with even lethal consequences. Toxic epidermal necrolysis is usually a drug-hypersensitivity syndrome. More than a hundred drugs were suspected to cause toxic epidermal necrolysis. Although benzodiazepines had been suspected in some cases, flurazepam has not been implicated thus far. The authors report a severe, life threatening case of toxic epidermal necrolysis in a young woman suffering from schizophrenia. The most probable cause was flurazepam, a hypnotic agent of the benzodiazepine class

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA