Naslov
Repeated presentation of Graves' disease as a manifestation of immune reconstitution syndrome in an HIV-infected patient taking HAART: case report

Autori
Višković, Klaudija, Stemberger, Lorna ; Brnić, Zoran ; Begovac, Josip

Izvornik
Acta clinica Croatica (0353-9466) 52 (2013), 1; 125-127

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
HIV infection ; Antiretroviral therapy ; Graves’ disease

Sažetak
An HIV-infected patient who experienced immune reconstitution after highly active antiretroviral therapy (HAART) (increase in CD4 T-cell count from 84/mm3 to 310/mm3) presented with severe Graves' disease twice, after commencing and recommencing HAART. At the first episode of Graves' disease, 21 months after the introduction of HAART, the symptoms of thyroid dysfunction vanished without any specific treatment, but were associated with termination of taking HAART. At the second episode, 5 years after recommencing HAART, the patient continued taking HAART and commenced antithyroid therapy with thiamazole. Graves' disease developed after a long period, while the patient was in good condition and when complications resulting from HAART were not expected. No features of any autoimmune disease were diagnosed before HAART initiation.

Izvorni jezik
Hrvatski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

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