Naslov
Therapeutic hypothermia for severe adult Herpes simplex virus encephalitis

Autori
Kutleša, Marko ; Baršić, Bruno

Izvornik
Wiener klinische Wochenschrift (0043-5325) 124 (2012), 23/24; 855-858

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
encephalitis; hypothermia

Sažetak
Despite antiviral treatment and advances in critical care, the Herpes simplex encephalitis (HSE) still has a poor outcome in a significant portion of patients. In severe cases of HSE, reduced carbon dioxide reactivity is usually present and these patients don't respond to the usual treatment of brain edema and intracranial hypertension. We present case series of patients with severe form of HSE treated with therapeutic hypothermia (TH) and describe in detail the indications, methods, and the rationale for its use. In this case series, patients presented with severely impaired consciousness and very high predicted death rate as measured by Glasgow coma scale and Acute Physiology and Chronic Health Evaluation (APACHE II) score respectively. According to our findings, TH in carefully selected patients with HSE holds promise as an adjunctive to the antiviral treatment.

Izvorni jezik
Engleski

POVEZANOST RADA