Pregled bibliografske jedinice broj: 668543
Uloga WNT u razvoju i funkciji bubrega
Uloga WNT u razvoju i funkciji bubrega // Acta medica Croatica. Supplement, 66 (2012), supplement2; 56-58 (podatak o recenziji nije dostupan, pregledni rad, stručni)
CROSBI ID: 668543 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Uloga WNT u razvoju i funkciji bubrega
(A role of WNT in kidney development and function)
Autori
Mesar, I ; Kes, P ; Jukić, NB
Izvornik
Acta medica Croatica. Supplement (1331-1638) 66
(2012), Supplement2;
56-58
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni
Ključne riječi
uloga glikoproteina WNT 4; nefrogeneza
(WNT 4 function; nephrogenesis)
Sažetak
WNT 4 is a secreted glycoprotein that is critical for nephrogenesis during mesenchymal to epithelial transformation. Lately there are some experimental modles witch confirm a role of Wnt 4 during regeneration process in acute renal failure. On the other hand there are some evidence that Wnt 4 plays important role in renal fibrosis during experimental renal injury in rats that provide tubuloinerstitial fibrosis. When will Wnt 4 have a protective role or when will induce fibrosis still is not known and therefore futher studies will be necessary to gain a more precise understanding.
Izvorni jezik
Hrvatski
POVEZANOST RADA
Projekti:
108-0000000-3499 - Prevencija, rano prepoznavanje i liječenje kroničnog zatajenja bubrega (Kes, Petar, MZOS ) ( CroRIS)
108-1080134-0122 - Čimbenici rizika za razvoj ateroskleroze nakon transplantacije bubrega (Bašić-Jukić, Nikolina, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb