Pregled bibliografske jedinice broj: 668508
Plasma ammonia concentrations in patients during chemotherapy
Plasma ammonia concentrations in patients during chemotherapy // Bichemia medica / Suchanek, Ernest (ur.).
Zagreb: Hrvatsko društvo za medicinsku biokemiju i laboratorijsku medicinu (HDMBLM), 2000. str. 89-89 (poster, međunarodna recenzija, sažetak, stručni)
CROSBI ID: 668508 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Plasma ammonia concentrations in patients during chemotherapy
Autori
Šupe, Daniela ; Čepić, Katarina ; Dujmov, Ivana ; Tocilj, Jadranka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Izvornik
Bichemia medica
/ Suchanek, Ernest - Zagreb : Hrvatsko društvo za medicinsku biokemiju i laboratorijsku medicinu (HDMBLM), 2000, 89-89
Skup
6th Alps-Adria congress of clinical chemistry and laboratory medicine
Mjesto i datum
Opatija, Hrvatska, 15.06.2000. - 17.06.2000
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
hyperammonemia ; urea synthesis ; chemotherapy
Sažetak
Ammonia is the primary breakdown product of amino acids and it is synthesised within all organs.Nitrogen, generated in the form of ammonia from the metabolism of amino acids is usually excreted in the form of urea.Disturbances of urea synthesis, with subsequent hyperammonemia could be result of:-severe liver disease(usually chirrhosis or other conditions:high-dose chemotherapy, valproic acid therapy or multiple myeloma)or-genetic disorders.We measured ammonia concentrations in 20 patients(range 25-69μmol/L), treated with high-dose chemotherapy.Hyperammoniemia was observed among 14 patients(range 34-69μmol/L), with strong symptoms of vomiting.Our results could emphasise the need of monitoring ammonia concentration in different chemotherapy cycles.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
