Naslov
Immune suppression of commercial broilers in Croatia, Slovenia, and Bosnia and Herzegovina from 1981 to 1991

Autori
Ragland, William Lauman ; Mazija, Hrvoje ; Cvelić- Čabrilo, Vesna ; Savić, Vladimir ; Novak, Renata ; Pogačnik, Milan

Izvornik
Avian pathology (0307-9457) 27 (1998); 200-204

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
immune suppression ; chicken anaemia virus ; chickens

Sažetak
A continuous decline in immune responses to Newcastle disease (ND) vaccine was observed in commercial broiler flocks in Croatia, Slovenia, and Bosnia and Herzegovina beginning in 1982. Floating mean haemagglutination inhibition (HI) titres declined from log2 4 in 1983 to a low of log2 2.4 in 1986, then were log2 2.9 in 1990. Several causes of the decline were discounted, leaving mycotoxins in feed and infection with chicken anaemia virus (CAV) as the two most likely causes. Mycotoxins in feed could nor be evaluated retrospectively, but archival tissues were available from Croatia and Slovenia. Tissue sections were examined by in situ hybridization for CAV. Whereas only one chicken from early in the decade was infected, all but one of the chickens from late in the decade were. The increase in CAV detection correlated inversely with ND HI titres. Whereas this correlation does not establish cause and effect, CAV cannot be eliminated as a contributory cause of immune suppression.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Veterinarska medicina

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