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Pregled bibliografske jedinice broj: 663490

Opioid system genes in alcoholism: A case–control study in Croatian population

Čupić, Barbara; Štefulj, Jasminka; Zapletal, Emilija; Matošić, Ana; Bordukalo-Nikšić, Tatjana; Čičin-Šain, Lipa; Gabrilovac, Jelka
Opioid system genes in alcoholism: A case–control study in Croatian population // Neuropeptides, 47 (2013), 5; 315-319 doi:10.1016/j.npep.2013.08.002 (međunarodna recenzija, članak, znanstveni)

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Naslov
Opioid system genes in alcoholism: A case–control study in Croatian population

Autori
Čupić, Barbara ; Štefulj, Jasminka ; Zapletal, Emilija ; Matošić, Ana ; Bordukalo-Nikšić, Tatjana ; Čičin-Šain, Lipa ; Gabrilovac, Jelka

Izvornik
Neuropeptides (0143-4179) 47 (2013), 5; 315-319

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
alcohol dependence; single nucleotide polymorphism; OPRM1; POMC; OPRK1; PDYN; Cloninger typology

Sažetak
Due to their involvement in dependence pathways, opioid system genes represent strong candidates for association studies investigating alcoholism. In this study, single nucleotide polymorphisms within the genes for mu (OPRM1) and kappa (OPRK1) opioid receptors and precursors of their ligands – proopiomelanocortin(POMC), coding for beta-endorphin and prodynorphin (PDYN) coding for dynorphins, were analyzed in a case–control study that included 354 male alcohol-dependent and 357 male control subjects from Croatian population. Analysis of allele and genotype frequencies of the selected polymorphisms of the genes OPRM1/POMC and OPRK1/PDYN revealed no differences between the tested groups. The same was true when alcohol-dependent persons were subdivided according to the Cloninger’s criteria into type-1 and type-2 groups, known to differ in the extent of genetic control. Thus, the data obtained suggest no association of the selected polymorphisms of the genes OPRM1/POMC and OPRK1/PDYN with alcoholism in Croatian population.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA

Projekti:
098-0982464-2520 - Uloga membranskih peptidaza na tumorskim i normalnim stanicama (Gabrilovac, Jelka, MZOS ) ( CroRIS)
098-1081870-2395 - Serotonergična neurotransmisija: geni, proteini i ponašanje (Štefulj, Jasminka, MZOS ) ( CroRIS)
098-1081870-2397 - Serotonergični mehanizmi u alkoholizmu (Čičin-Šain, Lipa, MZOS ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Ana Matošić (autor)

Avatar Url Jasminka Štefulj (autor)

Avatar Url Tatjana Bordukalo Nikšić (autor)

Avatar Url Jelka Gabrilovac (autor)

Avatar Url Emilija Zapletal (autor)

Avatar Url Lipa Čičin-Šain (autor)

Avatar Url Barbara Čupić (autor)

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com

Citiraj ovu publikaciju:

Čupić, Barbara; Štefulj, Jasminka; Zapletal, Emilija; Matošić, Ana; Bordukalo-Nikšić, Tatjana; Čičin-Šain, Lipa; Gabrilovac, Jelka
Opioid system genes in alcoholism: A case–control study in Croatian population // Neuropeptides, 47 (2013), 5; 315-319 doi:10.1016/j.npep.2013.08.002 (međunarodna recenzija, članak, znanstveni)
Čupić, B., Štefulj, J., Zapletal, E., Matošić, A., Bordukalo-Nikšić, T., Čičin-Šain, L. & Gabrilovac, J. (2013) Opioid system genes in alcoholism: A case–control study in Croatian population. Neuropeptides, 47 (5), 315-319 doi:10.1016/j.npep.2013.08.002.
@article{article, author = {\v{C}upi\'{c}, Barbara and \v{S}tefulj, Jasminka and Zapletal, Emilija and Mato\v{s}i\'{c}, Ana and Bordukalo-Nik\v{s}i\'{c}, Tatjana and \v{C}i\v{c}in-\v{S}ain, Lipa and Gabrilovac, Jelka}, year = {2013}, pages = {315-319}, DOI = {10.1016/j.npep.2013.08.002}, keywords = {alcohol dependence, single nucleotide polymorphism, OPRM1, POMC, OPRK1, PDYN, Cloninger typology}, journal = {Neuropeptides}, doi = {10.1016/j.npep.2013.08.002}, volume = {47}, number = {5}, issn = {0143-4179}, title = {Opioid system genes in alcoholism: A case–control study in Croatian population}, keyword = {alcohol dependence, single nucleotide polymorphism, OPRM1, POMC, OPRK1, PDYN, Cloninger typology} }
@article{article, author = {\v{C}upi\'{c}, Barbara and \v{S}tefulj, Jasminka and Zapletal, Emilija and Mato\v{s}i\'{c}, Ana and Bordukalo-Nik\v{s}i\'{c}, Tatjana and \v{C}i\v{c}in-\v{S}ain, Lipa and Gabrilovac, Jelka}, year = {2013}, pages = {315-319}, DOI = {10.1016/j.npep.2013.08.002}, keywords = {alcohol dependence, single nucleotide polymorphism, OPRM1, POMC, OPRK1, PDYN, Cloninger typology}, journal = {Neuropeptides}, doi = {10.1016/j.npep.2013.08.002}, volume = {47}, number = {5}, issn = {0143-4179}, title = {Opioid system genes in alcoholism: A case–control study in Croatian population}, keyword = {alcohol dependence, single nucleotide polymorphism, OPRM1, POMC, OPRK1, PDYN, Cloninger typology} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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